In July 2015, Spotz took 1st place as the overall female winner in the Olympic distance race. Read more here.

In May 2015, Spotz qualified for the Boston Marathon with a time of 3:27 at Buffalo Marathon and placed 3rd in her age-group.

In August 2014, Spotz placed top ten in her age group with a time of 11:36. She raised more than $11,000 for water projects in India.

In September 2013, Spotz placed 1st in her division and 2nd overall female, with a time of 10:48 for the 2.4-mile swim, 112-mile bike, and 26.2-mile run.

In June 2011, Spotz and her team completed the 3,000-mile relay bicycle Race Across America in less than eight days, cycling 24/7. Amazingly, Katie broke her pelvic while training the week before the race, but went on to compete using a hand-cycle.

In May 2011, Spotz cycled 375-miles in 24 hours with nearly 20,000 feet of climbing. This was part of the San Francisco Randonneurs 600K Fort Bragg Brevet, a long-distance unsupported event.

In March 2010, Spotz set the world record as the youngest person to row solo across the Atlantic Ocean, rowing 3,038 miles from West Africa to South America. More than $150,000 was raised for clean water projects as the mission behind the row.

In August 2008, Spotz became the first and only person to swim the entire 325-mile length of the Allegheny River ‒ swimming 12 to 15 miles a day, 6 to 8 hours a day for a month.

From June to August 2006, she cycled 3,300 miles across the United States from Seattle to D.C., averaging 85 miles a day for 40 days. Together, with 40 other cyclists, they raised more than $250,000 for the American Lung Association.